Applikon is one of the most reputed manufacturer of Fermentor / Bioreactor systems since 1973

	Applikon provides you a wide range of Fermentor / Bioreactor systems in working volume ranges from 50 µl upto 1500L or Higher scales.

Micro 24 : Micro Bioreactor - High Throughput Fermentation and Cell Culture Device, 24 controlled bioreactors working in parallel in the space of a Notebook Computer.

	All 24 Bioreactors have their own independent pH, DO and temperature settings. Fastest Optimization !!

Autoclavable glass bioreactors / fermentors ranging from 1 to 20 liters

	The eZ control. Latest Generation state-of-the-art, Self tuning / Adaptive Controller.
	Easily convertible systems from Microbial Fermentation to Cell Culture or Vise-e-versa
	Flexible configuration for fast adaptation.

Steam In Place (SIP) stainless steel Labscale bioreactors ranging from 7 to 30 liters

	In-Situ sterilizable systems, which again offer a flexible configuration.
	Both C.I.P. and S.I.P options available on the lab scale systems
	One of the best surface finish on the vessels in the world – Surface roughness average Ra < = 0.4 µm

Single use Bioreactors – Appliflex

	Only systems in the world which can have either single use sensors or re-usable sensors ( Save Costs !! )
	Available in working volume ranges of 2 L to 50 Liters ( bags available from applikon )
	The eZ control offers one of the best control on all parameters.

Pilot scale (Sip & CIP) Bioreactors ranging from 40 – 200

	Working volume ranges from 40 – 200 Liters are standard Systems
	Fully Automated / Semi Automated systems both for Microbial and Cell Culture Cultivation
	C.I.P. & S.I.P.

Project scale (Sip & CIP) Bioreactors / fermentors ranging from 200 Liters upto 1500 Liters or Higher Capacities.

	Semi Automated and or Fully Automated systems.

ON-Line OD Monitor / Biomass Monitor

	Real time Biomass Concentration is measured as a function of Near Infra Red Absorption. On-Line display of OD
	Available for both types of Fermentors– Autoclavable / In-situ sterilizable
	Unique design of sensors – No potential Clogging

Aber Biomass Monitor

	Aber biomass monitor is a sophisticated option offered with Applikon fermentors. This biomass monitor can give you only the density of living cells, excluding the dead cells. Thus, you can finally know the density of living cells that truly determine the production from your fermentation process.

Real time O₂, CO₂ Analyzer can be connected Directly to the Fermentor. It does not require any additional Pump or valve.

	The sensors are not effected by Humidity or gases coming out of the Bioreactor, Hence no seperate heating system is required on the exhaust line.
	O2 Sensor based on paramagnetic sensing
	CO2 Sensor based on IR.

The Unique Perfusion System - BioSep

	The BioSep is an innovative tool for perfusion of mammalian cells and is a unique cell retention device for high-density perfusion processes
	Using high frequency resonant ultrasonic waves to separate cells instead of a physical mesh or membrane, it offers all the benefits of traditional devices but without their persistent problems.
	Available in 3 Volumes of Perfusion – 10 Liters per day / 50 Liters per day / 200 Liters per day (Rule of thumb – Perfuse twice the working volume in one day)
	Soon arriving a BioSep with a Perfusion rate of 1000 Liters per day !!

Weight Based Feed Control system for Fed Batch Processes

Feed Master

	The feed master is an excellent unit for programmed and controlled nutrient feed.
	The mechanism holds fit for both culture regeneration where micro volumes as slight as 0.4 gms / min with an accuracy of +/- 0.1 gms / min are needed as also during experimental processes where macro volume levels as high as 200 gms / min. or even more are desired.

ARE YOU LOOKING FOR THE RIGHT SOLUTION IN ONLINE MEASUREMENT?
YES, WE OFFER A COMPLETE RANGE OF SENSORS (pH & DO) COMPATIBLE WITH ALL SIZES
AND MAKES OF FERMENTOR SYSTEMS

Applikon offers high quality sensors, with the appropriate application know-how,to the world wide biotechnology market, the pharma industry and the food & Agro industry world wide. Applikon holds two decades of expertise and experience in On-Line measuring and control. Applikon is linked to leading universities, R & D institutes and manufacturers of On-Line analysis devices.

We Offer :
 Extensive know-how of applications in biotechnology
 Complementary sensor technology

The Sensor we Offer :

1. Refillable pH Sensors

	High isolation resistance in the connector is maintained even after repeated sterilizations
	Extreme stability of zero point and slope even after repeated sterilization Correction of the pH value after sterilization is not required.
	The reference cartridge provides a conditioned environment offering good sensor stability.
	High accuracy due to continuous outflow of electrolyte.

2. Gel Filed Sensor

	Use of non-Toxic gel.
	Resistant against vacuum (during autoclaving).
	Perfect isolation against electromagnetic disturbance from the environment.
	Performance as refillable.
	Low Maintenance.

3. Low Drift DO Sensor

	Available with a titanium module (patentedP, This offers a guarantee low drift.
	An investment, not a consumable
	Fully electro polished surface (Ra<0.8nm)

The first Complete system for maintenance, replication & Growth of Microbial Strains in 96 well micro Titer plates.

Features :

	Spring-loaded replicator for the simultaneous and reproducible sampling of 96 frozen glycerol stocks.
	An investment, not a consumable
	A single master plate can be used more than 100 times sandwich covers convert all 96 wells of a deepwell plate into individual “mini-reactors” with identical properties.
	Oxygen transfer rates and KLA values during orbital shaking similar to those in Erlenmeyer flasks.
	No cross-contamination.
	Low and uniform evaporation rates.
	Various aerobic strains grow to cell densities of 10 g dry wt l-1.
	Designed for use with heterogeneous strain collections of aerobic bacteria and streptomycetes, but also applicable for clonal libraries n E. coli or yeasts.

Photo Bioreactor

	Photo Bioreactor with Controlled and programmable Illumination system for growing algae / plant cells in the Bioreactor
	This photobioreactor boasts of EMI-radiation-free light and can be programmed into EIGHT different time and intensity zones. Contact us now to know more about this illuminated bioreactor system!
	Mist Fermentor is also available for Hairy Root